COMBINED TREATMENT OF HCV INFECTIONS IN PRISONERS WITH PEGFERON AND REBETOL

Аннотация

 Hepatitis C is one of the mostly spread disease worldwide  causing chronic inflammation of liver-hepatitis, liver cirrhosis and hepatocellular cancer. The evidence of infections caused by HCV in Georgia is the highest, among that hepatitis C is the most challenging problem of healthcare in Georgia. 2010 prisoners with hepatitis C are under observation. The inclusion criteria are: Age (>18 y) in patients of  both gender, who has anti HCV  ELIZA active hepatitis  C confirmed with HCN RNA chain polymerase reaction. The majority of patients (95%) are males, their average age is 25-45 y (71%). The cytolysis syndrome is frequent (increased activity of ALT, AST, GGT) in most of them AST>ALT (which indicates severe form of disease). In 2/3 of patients the level of common bilirubin is increased. More than half  of patients have decreased level of albumine in blood. The level of glucose in blood is also important mostly in genotype III infected patients (its twice as often) compared with genotype I and II. In 2/3 of patients the high and very high viremia was found irrespective of genotypes.