Pathogenesis of renal osteodystrophy

How to Cite

Topuridze, M., Pavliashvili, N., Katsadze, M., Namoradze, M., & Delibashvili, D. (2026). Pathogenesis of renal osteodystrophy. Collection of Scientific Works of Tbilisi State Medical University, 57. Retrieved from https://journals.4science.ge/index.php/CSW/article/view/4745

Abstract

Chronic kidney disease is characterized by a peculiar damage of bone tissue - renoprival osteodystrophy, with osteoporosis and osteomalacia. This is due to the active participation of the kidney in the exchange of minerals necessary for bone and in the metabolism of hormones involved in this process. Also by synthesizing certain proteins (Klotho, BMP), the kidney plays an important role in the process of bone remodeling. By itself, acid-alkaline imbalance, which occurs during chronic kidney pathologies, contributes to bone tissue dysfunction.

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