Abstract
Neuroplasticity refers to the inherently dynamic biological capacity of the central nervous system (CNS) to undergo maturation, change structurally and functionally in response to experience and to adapt following injury. This malleability is achieved by modulation subsets of genetic, molecular and cellular mechanisms that influence the dynamics of synaptic connections and neural circuitry formation culminating in gain or loss of behavior or function.In this article we have reviewed different patterns of neuroplasticity under normal and abnormal conditions, explore the unique feature of “critical and sensitive periods” that govern the temporal and spatial profile of neuroplasticity in the developing brain.
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