Abstract
Epilepsy is one of the most common disorder in children causing neurodevelopmental disability. Beyond the repetitive seizures psychiatric, cognitive and social issues are the main challenges leading to a severe worsening of quality of life of affected children and their family members. The leading neuropsychiatric disorders coexisting with epilepsy are: attention deficit hyperactivity disorder (ADHD), autistic spectrum disorders (ASD), anxiety and depression, psychosis. The article reviewed the main issues of how to diagnose and manage children with epilepsy and comorbid neuropsychiatric disorders in order to avoid "diagnostic overlapping" which is the main reason for undiagnosed cases. It is necessary to initiate neurobehavioral screening in children with newly diagnosed epilepsy in order to avoid any ignorance of such important comorbidities.
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