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Abstract
The aim of the research was to estimate the effectiveness of nonorganic ferment(enzyme)Enfin Forte during the treatment of patients with pancreatic exocrine function failure. 42 patients with the diagnoses of chronic pancreatitis on exacerbation stage were observed. The patients age ranged from 18 to 75 years. Duration of the disease ranged from 3 to 10 years. The patients had 2 to 6 relapses of the disease per year. It has been revealed that nonorganic drug Enfin Forte which is resistant to the human and animal pancreatic gland enzyme inhibitors had shown high clinical effectiveness in patients with pancreatic exocrine insufficiency. It isn’t necessary to prescribe the drug at the time of each meal. Enfin forte is effective when taken only once a day.
References
2. Riley S.A.,Marsh M.N. Maldigestion and malabsorption. Sleisinger and Fordtran’s gasrrointestinal and liver disease. Edit.by Feldman M.,Scharschmidt M., Sleisenger M.H. 6th .ed 1998.
3. Banks P.A. Acute and chronic pancretitis. Sleisinger and Fordtran’s gasrrointestinal and liver disease. Edit.by Feldman M.,Scharschmidt M., Sleisenger M.H. 6 .ed 1998.
4.Opekun AR.,Sutton F.M., Lack of dose-response with Pancrease MT for the treatment of exocrine pancreatic insufficiency in adults. Aliment. Pharmacol.Ther. 1997. Oct.. Vol11,5 p 981-986.
5.Lankisch P.G.,Banks P.A. Pancreatitis. SpringerVerlag:Berlin,Heidelberg,1998.p 377.
6.Roberts I.M.Enzyme Therapy for malabsorbtion in exocrine pancreatic insufficiency. –Pancreas.-1989. Vol 4. p.496-503.
7. Layer P., Groger G.Fate of Pancreatic Enzymes in the Human Intestinal Lumen in Health and Pancreatic Insufficiency //Digestion.- 1993.- Vol. 54, Suppl. 2.— P. 10—14.
8. . Johnson C.D., Imrie C.W. Pancreatic disease: basic science and clinical management.— London et al. : Springer_Verlag, 2004.— 490 p.
9. Chronic Pancreatitis : Novel concepts in biology and therapy / Ed. M.W. Buchler et al. — Berlin; Wien: Wissenschafts_Ver_lag; A Blackwell Publishing Company, 2002.— 614 ð.
10.Lohr j.-M Exocrine pancreatic insufficiency.-1 ed.Bremen:UNI-Med,2007.-71.