The role of perinatal genetic screening in predicting pregnancy outcome
DOI:
https://doi.org/10.52340/spectri.2023.06Keywords:
pregnancy, premature birth, genome, prenatal genetic screeningAbstract
Pregnancy is one of the main stages of a woman's life cycle, its full-fledged and physiological management is important both for the future mother and the embryo. This or that pathological condition of the perinatal period finds an echo not only on the pregnant woman and the embryo, but also on the newborn, in the neonatological or adult age, which affects the etiology and pathogenesis of a number of diseases. Premature birth is the most common pathological condition among many others, which is evidenced by the high and increasing prevalence worldwide. The paper analyzes the literary sources, discusses in detail the genetic determinants of the etiopathogenesis of spontaneous premature birth, the changes of which can be detected by prenatal genetic screening. The paper suggests the role of the latter in the process of predicting the outcome of pregnancy.
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