AUTOLOGOUS ADIPOSE-DERIVED STEM CELL THERAPY IN ORTHOPEDIC SURGERY: CURRENT CONCEPTS AND CLINICAL APPLICATIONS

TORNIKE AVALISHVILI

doi:10.52340/jecm.2026.03.03

Authors

TORNIKE AVALISHVILI Aversi Clinic, Tbilisi, Georgia

DOI:

https://doi.org/10.52340/jecm.2026.03.03

Keywords:

adipose-derived, stem cells, liposuction, regenerative medicine, orthopedics

Abstract

This review provides a concise and up-to-date overview of the biological basis and clinical applications of autologous adipose-derived stem cell therapy in orthopedic surgery. The manuscript summarizes current evidence regarding the use of adipose-derived mesenchymal stromal cells in knee osteoarthritis, cartilage defects, meniscal injuries, and tendinopathies while addressing their mechanisms of action, safety profile, and current limitations. Although further high-quality randomized controlled trials are required, the review highlights the promising role of ADSC-based therapies as a biological adjunct in modern regenerative orthopedics.

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