Zn AND Cu LEVELS IN THE BLOOD PLASMA IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER (ADHD) WHOSE MOTHERS SMOKED DAILY DURING PREGNANCY

Zn AND Cu LEVELS IN THE BLOOD PLASMA IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER (ADHD) WHOSE MOTHERS SMOKED DAILY DURING PREGNANCY

Authors

  • ANA CHOCHIA Tbilisi Balneological Resort, Georgia
  • DAVID ZURABASHVILI Center for Mental Health and Prevention of Addiction, Tbilisi, Georgia
  • NANA KAPANADZE Tbilisi State Medical University image/svg+xml

DOI:

https://doi.org/10.52340/jecm.2025.04.02

Keywords:

microelements, Zn, Cu, ADHD, blood plasma

Abstract

It was determined Zn and Cu level in the blood plasma in children with ADHD syndrome, whose mothers smoked constantly during pregnancy. The obtained data were compared with the data of children with ADHD, whose mothers never smoked during pregnancy. Zinc deficiency was detected in the blood plasma of all the examined children. The decrease in Zn level was more pronounced in children whose mothers smoked during pregnancy. Cu level in the blood plasma corresponded to age standards in all the examined children. It is necessary to differentiate the cause-and-effect relationships involved in the development of behavioral disorders (local or specific).

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Author Biographies

ANA CHOCHIA, Tbilisi Balneological Resort, Georgia

Tbilisi Balneological Resort, Georgia

Center for Mental Health and Prevention of Addiction, Tbilisi, Georgia

DAVID ZURABASHVILI, Center for Mental Health and Prevention of Addiction, Tbilisi, Georgia

Center for Mental Health and Prevention of Addiction, Tbilisi, Georgia

I. Javakhishvili Tbilisi State University, Georgia

References

Badru A.A., Kukoyi B.I., Ukponmwan O.E. Some effects of zinc on maternal and fetal integrity in pregnancy. Nigerian Journal of Physiological Sciences. 2006,21(1-2); 91-97.

Baek M., Chung H.E., et al. Pharmacokinetics tissue distribution and excretion of zinc oxide nanoparticles. Int.I: Nanomedicine. 2012,7:3081-3097.

Gabunia A. et al. Adaptation of the Strength and Difficulties Questionnaire for use in the Republic of Georgia Original Article. Alpha Psychiatry. 2023;24(4):128-135.

Oberlis D., Harland B., Skalny A. The biological role of macro- and microelements for humans and animals. St. Petersburg; Nauka: 2018; 554p.

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Published

2025-08-21

How to Cite

CHOCHIA, A., ZURABASHVILI, D., & KAPANADZE, N. (2025). Zn AND Cu LEVELS IN THE BLOOD PLASMA IN CHILDREN WITH ATTENTION DEFICIT AND HYPERACTIVITY DISORDER (ADHD) WHOSE MOTHERS SMOKED DAILY DURING PREGNANCY. Experimental and Clinical Medicine Georgia, (4), 11–13. https://doi.org/10.52340/jecm.2025.04.02

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