SIDE EFFECTS OF DRUGS, WAYS TO AVOID THEM AND PREVENT DRUG-RELATED COMPLICATIONS

SIDE EFFECTS OF DRUGS, WAYS TO AVOID THEM AND PREVENT DRUG-RELATED COMPLICATIONS

Authors

DOI:

https://doi.org/10.52340/jecm.2023.04.50

Keywords:

drugs, side effects, drug-related complications, START/STOPP criteria

Abstract

Adverse reactions to medications are one of the most common problems for doctors and are often the cause of hospitalization. More often, adverse side effects develop as a result of the use of the following pharmacological groups: oral anticoagulants, cardiac glycosides, oral hypoglycemic agents, statins, aspirin, paracetamol, amiodarone, antidepressants. The "START/STOPP" criteria, developed in Ireland in 2008 by 19 experts from 13 European countries, provide recommendations based on high scientific evidence on the dangers and risks associated with the use of drugs, pharmacological groups in clinical practice for various diseases and symptoms.

The main aspects of rational drug prescription are: making an appropriate diagnosis; consideration

of the pathophysiological results of the diagnosis; selection of a specific therapeutic strategy; Selection of a specific drug of choice; determining the appropriate dosage regimen; Developing a plan for monitoring the action of the drug and determining the course of therapy or treatment. The main directions of the best prescription and clinical practice are the selection of the most effective and harmless drug/drug combination, patient supervision, prevention of side effects of drugs and drug-related complications on the basis of periodic monitoring of appropriate ambulatory or instrumental examinations.

Downloads

Download data is not yet available.

References

Somers A., Mallet L., Vander Cammen T., Robays H., Petrovic M. Applicability of anadapted medication appropriateness index for detection of drug-related problems in geriatric inpatients//TheAmerican Journal of Geriatric Pharmacotherapy. 2012.10(2):101109.

Lund B.C., Carnahan R.M., Egge J.A., Chrischilles E.A., Kaboli P.J. Inappropriate prescribing predicts adverse drug events in older adults//The Annals of Pharmacotherapy.2010;44:957–963.

Patterson S.M., Hughes C., Kerse N., Cardwell C.R., Bradley M.C. Interventions to improve the appropriate use of polypharmacy for older people//Cochrane Data base of Systematic Reviews. 2012, May.5: CD008165. DOI:10.1002/14651858.CD008165.pub2.

O’Connor MN. Adverse drug reactions in older people during hospitalization: prevalence, risk factors and recognition. Unpublished MD thesis. University College Cork, 2013.

Sutherland J. J. et al. Co-prescription trends in a large cohort of subjects predict substantial drug-drug interactions. PLoS ONE 10, 3 (2015).

Johnell K. & Klarin I. The relationship between number of drugs and potential drug-drug interactions in the elderly: a study of over 600,000 elderly patients from the Swedish Prescribed Drug Register. Drug Saf. 30, 911–918 (2007).

Payne R. A. The epidemiology of polypharmacy. Clin.Med. 16, 465–469 (2016).

Rambhade S., Chakarborty A., Shrivastava A., Patil U. K. &Rambhade A. A survey on polypharmacy and use of inappropriate medications. Toxicol. Int 19, 68–73 (2012).

Kessler C., Ward M. J. & McNaughton C. D. Reducing Adverse Drug Events: The Need to Rethink Outpatient Prescribing. JAMA 316, 2092–2093 (2016).

Qato D. M., Wilder J., Schumm L. P., Gillet V. & Alexander G. C. Changes in Prescription and Over-the-Counter Medication and Dietary Supplement Use Among Older Adults in the United States, 2005 vs 2011. JAMA Intern.Med. 176, 473–482 (2016).

Ward B. W., Schiller J. S. & Goodman R. A. Multiple Chronic Conditions Among US Adults: A 2012 Update. Prev. Chronic Dis 11, E62 (2014).

Jirón M. et al. Trends in Prevalence and Determinants of Potentially Inappropriate Prescribing in the United States: 2007 to 2012. J. Am. Geriatr. Soc 64, 788–797 (2016).

Gabunia L., The Document of Polypharmacy. Tbilisi, Georgia. 2018.

Downloads

Published

2023-11-29

How to Cite

GABUNIA, L., RATIANI, L., GORGASLIDZE, N., & VARAZI, G. (2023). SIDE EFFECTS OF DRUGS, WAYS TO AVOID THEM AND PREVENT DRUG-RELATED COMPLICATIONS . Experimental and Clinical Medicine Georgia, (4), 224–228. https://doi.org/10.52340/jecm.2023.04.50

Issue

Section

Articles

Most read articles by the same author(s)

1 2 > >> 

Similar Articles

<< < 3 4 5 6 7 8 9 10 11 12 > >> 

You may also start an advanced similarity search for this article.

Loading...