ASSOCIATION OF UTERINE PROLAPSE SYMPTOMS WITH BODY MASS INDEX
Keywords:uterine prolapse, pelvic organ prolapse, body mass index, PFDI-20 questionnaire, correlation
Understanding the impact of obesity on pelvic organ prolapse is important. Objective: To evaluate the association between obesity and uterine prolapse in 108 women with uterine prolapse. The degree of prolapse was determined by the POP-Q system. The PFDI-20 questionnaire, POPDI-6, CRADI-8, UDI-6 subscales were used. Calculated body mass index BMI. The average age of patients was 44.11±4.38 years. Stage I prolapse was noted in 28.7%, stage II - in 49.1%, stage III - in 18.5%, stage IV - in 3.7% of patients. The total score on the questionnaire was 95.58±25.0. POPDI-6 - 46.31±11.32, CRAD-8 - 19.17±6.17 and UDI-6 - 32.59±10.27 points. The average BMI was 24.88±3.22 kg/m2. Taking into account the value of BMI, the patients were divided into 2 groups: group I - 53 (49.1%) patients with BMI 29.9 - 33.6 kg / m2, group II - 55 (50.9%) patients with BMI 19.3- 29.8 kg/m2. In group I, patients aged 25-35 years were much less common (p=0.002) and patients aged 46-55 years were significantly more common (p<0.001). In group II, normal BMI occurred in 87.3% of cases (p<0.001), overweight - in 12.7% of cases (p=0.374). In obese patients, BMI correlated with uterine prolapse scores in a weak, direct, but statistically non-significant relationship. According to the results of a prospective study, it was found that in women with uterine prolapse and obesity with stages II and III of uterine prolapse, the body mass index is higher than in stage I. Obesity correlates with uterine prolapse by a weak, direct, statistically insignificant relationship.
de Arruda GT, dos Santos Henrique T, Virtuoso JF. Pelvic floor distress inventory (PFDI)—systematic review of measurement properties. Int Urogynecol J. 2021;32:2657–2669. doi: 10.1007/s00192-021-04748-4.
Askerova MSh, Rzakulieva LM. Prevalence and risk factors for pelvic organ prolapse in female citizens of Baku. Kazan Medical Journal.2018;99(2):187-194. doi: 10.17816/KMJ2018-187.
Asresie A, Admassu E, Setegn T. Determinants of pelvic organ prolapse among gynecologic patients in Bahir Dar, North West Ethiopia: a case–control study. Int J Women's Health. 2016;8:713–719. doi:10.2147/IJWH.S122459.
Bohlin KS, Ankardal M, Nüssler E, Lindkvist H, Milsom I. Factors influencing the outcome of surgery for pelvic organ prolapse. Int Urogynecol J. 2018;29(1):81–89. doi: 10.1007/s00192-017-3446-9.
Danilina OA, Volkov VG. Prevalence of pelvic organ prolapse among women of reproductive age. Journal of New medical technologies (Russia). 2022;29(1):29–33. doi: 10.24412/1609-2163-2022-1-29-33.
Devkota HR, Sijali TR, Harris C, Ghimire DJ, Prata N, Bates MN. Bio-mechanical risk factors for uterine prolapse among women living in the hills of west Nepal: A case-control study. Womens Health (Lond). 2020;16:1745506519895175. doi: 10.1177/1745506519895175.
Fitz FF, Bortolini MAT, Pereira GMV, Salerno GRF, Castro RA. PEOPLE: Lifestyle and comorbidities as risk factors for pelvic organ prolapse-a systematic review and meta-analysis PEOPLE: Pelvic Organ Prolapse Lifestyle comorbidities. Int Urogynecol J. 2023. doi: 10.1007/s00192-023-05569-3.
Gava G, Alvisi S, Mancini I, Seracchioli R, Meriggiola MC. Prevalence of metabolic syndrome and its components in women with and without pelvic organ prolapse and its association with prolapse severity according to the Pelvic Organ Prolapse Quantification system. Int Urogynecol J. 2019;30(11):1911-1917. doi: 10.1007/s00192-018-3840-y.
Giri A, Hartmann KE, Hellwege JN, Edwards DRV, Edwards TL Obesity and pelvic organ prolapse: a systematic review and meta-analysis of observational studies. American journal of obstetrics and gynecology.2017;217(1):11-26. e3. doi: 10.1016/j.ajog.2017.01.039.
Gray T, Money-Taylor J, Li W, Farkas AG, Campbell PC, Radley SC. What Is the Effect of Body Mass Index on Subjective Outcome Following Vaginal Hysterectomy for Prolapse? Int Neurourol J 2019; 23(2): 136-143. doi: 10.5213/inj.1938016.008.
Henok A. Prevalence and factors associated with pelvic organ prolapse among pedestrian back-loading women in bench Maji Zone. Ethiop J Health Sci. 2017;27(3):263–272. doi: 10.4314/ejhs.v27i3.8.
Kim BH, Lee SB, Na ED, Kim HC. Correlation between obesity and pelvic organ prolapse in Korean women. Obstetrics & Gynecology Science 2020;63(6):719-725. doi: 10.5468/ogs.19075.
Lee UJ, Kerkhof MH, van Leijsen SA, Heesakkers JP. Obesity and pelvic organ prolapse. Curr Opin Urol. 2017;27(5):428-434. doi: 10.1097/MOU.0000000000000428.
Liu H, Wu W, Xiang W, Yuan J. Lifestyle factors, metabolic factors and socioeconomic status for pelvic organ prolapse: a Mendelian randomization study. Eur J Med Res. 2023;28(1):183. doi: 10.1186/s40001-023-01148-w.
Madhu Ch, Swift S, Moloney-Geany S, Drake MJ. How to use the Pelvic Organ Prolapse Quantification (POP-Q) system? Neurology Urodynamics/ 2018;37(S6):S39-S43. doi: org/10.1002/nau.23740.
World Health Organization. WHO NCD Lab webinar: implementing grassroots innovations to tackle obesity. 2022, December.
Young N, Atan IK, Rojas RG, Dietz HP. Obesity: how much does it matter for female pelvic organ prolapse? International urogynecology journal. 2018;29(8):1129-34. doi: 10.1007/s00192-017-3455-8.
Zenebe CB, Chanie WF, Aregawi AB, Andargie TM, Mihret MS. et al. The effect of women’s body mass index on pelvic organ prolapse: a systematic review and meta-analysis. Reprod Health. 2021;18:45. doi: 10.1186/s12978-021-01104-z.