DETECTION OF GASTRIC CANCER AT A LATE STAGE AS AN IMPORTANT FACTOR AFFECTING THE SURVIVAL OF PATIENTS

DETECTION OF GASTRIC CANCER AT A LATE STAGE AS AN IMPORTANT FACTOR AFFECTING THE SURVIVAL OF PATIENTS

Authors

  • SABA ZHIZHILASHVILI
  • IRAKLI MCHEDLISHVILI
  • NANA MEBONIA
  • ANNA ZHIZHILASHVILI
  • MAIA KERESELIDZE

DOI:

https://doi.org/10.52340/jecm.2022.07.27

Keywords:

gastric cancer, survival analysis, stage, mortality

Abstract

The study aims to assess the possible correlation between the gastric cancer (GC) stage at the detection and survival of patients in 2015-2020 in Georgia.

Methods. Bivariable survival Analysis using Cox’s regression model was constructed. A hazard (mortality) ratio (HR) was estimated by the stage at detection of GC. The level of statistical significance of the study findings is estimated by using the 95% of confidence interval (95%CI).

Results. Totally 2242 GC patients were enrolled in the study. Bivariate statistical analysis has revealed that the risk of early mortality from GC detected at the fourth (HR=4.8; 95%CI=3.3-6.8) and second (HR=1.9; 95%CI=1.3-2.7) or third (HR=2.2; 95%CI=1.5-3.2) stages is almost 5 and 2-times higher accordingly in comparison to cancer detected at the first stage.

Conclusions. A high proportion of GC cases are detected at the late stage in Georgia which is the main predictor of patients’ early mortality.

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References

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Published

2022-10-27

How to Cite

ZHIZHILASHVILI , S. ., MCHEDLISHVILI , I. ., MEBONIA , N. ., ZHIZHILASHVILI, A. ., & KERESELIDZE , M. . (2022). DETECTION OF GASTRIC CANCER AT A LATE STAGE AS AN IMPORTANT FACTOR AFFECTING THE SURVIVAL OF PATIENTS . Experimental and Clinical Medicine Georgia, (7). https://doi.org/10.52340/jecm.2022.07.27

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