The Effect of Mineral Salts on the Antimicrobial Activity of Actinomycetes

Magda Davitashvili; Lamara Zuroshvili; Darejan Margalitashvili

doi:10.52340/idw.2025.05

The Effect of Mineral Salts on the Antimicrobial Activity of Actinomycetes

Authors

Magda Davitashvili Iakob Gogebashvili State University
Lamara Zuroshvili Iakob Gogebashvili State University
Darejan Margalitashvili Iakob Gogebashvili State University

DOI:

https://doi.org/10.52340/idw.2025.05

Keywords:

actinomycetes, mineral salts, antimicrobial activity, phytopathogenic bacteria, biotechnology

Abstract

This study aims to investigate the effect of different concentrations (from 1% to 5%) of mineral salts (NaCl, MgSO₄, CaCO₃, K₂HPO₄, KNO₃) on the antimicrobial activity of actinomycete strains (25, 57, and 124) in CPI-glucose nutrient media. To assess antagonistic activity, seven phytopathogenic bacteria were used in the agar disk diffusion method, and the diameter of the inhibition (sterile) zone was measured in millimeters.

The results showed that salt composition significantly determines the antimicrobial properties of the actinomycetes. In particular, strain 57 exhibited high activity under optimal MgSO₄ concentration conditions, whereas its bioactivity was significantly reduced at elevated levels of K₂HPO₄ and NaCl. In the case of CaCO₃, no significant changes in activity were observed, while for the other strains (25 and 124) only minor differences were noted. The study highlights the importance of the chemical characteristics of the environment that directly affect the efficacy of antimicrobial agents and suggests the biotechnological realization of the biological potential of actinomycetes in agriculture.

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