How to Cite

Saganelidze, T., Vepkhvadze, N., & Kochoradze-Margishvili, T. (2023). IONIZING RADIATION AND HEALTH . Collection of Scientific Works of Tbilisi State Medical University, 56, 124–128. Retrieved from


Scientific literature provides copious evidence on adverse health effects of exposure to ionizing radiation. Nevertheless, despite an abundance of research, conflicting data still exist. Nowadays, there’s undisputed opinion on negative health effects of high-dose radiation exposure.  Although there’s shortage of convincing data and unanimity of opinion on exposure to low-dose radiation and associated health risks. Present work is a short review of data around the given issue. Research on the effects induced by exposure to ionizing radiation proves that high-dose ionizing radiation has detrimental impact on human health. Nevertheless, there’s no common opinion among scientists on the effects of low-dose radiation despite widely known linear no-threshold model and stochastic effects for which no exposure threshold levels exist. Taking into account above mentioned, best means of avoiding possible harmful effects of radiation exposure must be unwavering adherence to guiding principle of radiation safety (“ALARA” – “as low as reasonably achievable”) meaning avoiding exposure to radiation that does not have a direct benefit even if the dose is small.



gelaSvili k., vefxvaZe n., kilaZe n. radiaciuli higiena. 2014. 242 gv.;

Abalo, Kossi D., Rage, Estelle; Leuraud, Klervi; Richardson, David B.; Le Pointe, Hubert Ducou; Laurier, Dominique; Bernier, Marie-Odile. Early life ionizing radiation exposure and cancer risks: systematic review and meta-analysis.Pediatric Radiology. Open Access. Volume 51, Issue 1, Pages 45 – 56, January 2021. = inward&txGid = 364c046ed6aa 3c918b9b25 cc6ed6f40b;

Ben D Spycher, Judith E Lupatsch, Marcel Zwahlen,Martin Röösli, Felix Niggli, Michael A Grotzer, Johannesm Rischewski, Matthias Egger, Claudia E Kuehni, Swiss Pediatric Oncology Group; Swiss National Cohort Study Group.Background ionizing radiation and the risk of childhood cancer: a census-based nationwide cohort study. Environ Health Perspect. 2015 Jun;123(6):622-8. doi: 10.1289/ehp.1408548.Epub 2015 Feb 23. PMID: 25707026 PMCID: PMC4455589 DOI: 10.1289/ehp.1408548.;

Ionizing radiation, health effects and protective measures.;

Joachim Schüz, Friederike Erdmann. Environmental Exposure and Risk of Childhood Leukemia: An Overview.Arch Med Res. 2016 Nov;47(8):607-614. doi: 10.1016/j.arcmed.2016.11.017.;

Joseph Y Allen, MDJohn R Wingard, MDNicholas Dainiak, MD, FACP. Management of radiation injury. Oct.2022. t r e a t m e n t - o f - r a d i a t i o n - i n j u r y - i n - t h e - adult&sp=0&searchType= PLAIN_TEXT&source=USER_INPUT & searchControl= TOP_PULLDOWN&searc hOffset =1&autoComplete=false&language= &max= 0&in-

dex= &autoComplete Term=#H57;

Julie Lopes, Clémence Baudin, Klervi Leuraud, Dmitry Klokov & Marie-Odile Bernier. Ionizing radiation exposure

during adulthood and risk of developing central nervous system tumors: systematic review and meta-analysis. Nature, Scientific Reports volume 12, Article number: 16209(2022).;

Justine Berlivet, Denis Hémon, Énora Cléro, Géraldine Ielsch, Dominique Laurier, Sandra Guissou, Brigitte Lacour,Jacqueline Clavel, Stéphanie Goujon. Ecological association between residential natural background radiation exposure and the incidence rate of childhood central nervous system tumors in France, 2000-2012. J Environ Radioact. 2020 Jan;211:106071. doi: 10.1016/j.jenvrad.2019.106071. Epub 2019

Oct 7.;

Luís Antunes, Maria José Bento, Manuel SobrinhoSimões, Paula Soares, and Paula Boaventura. Cancer incidence after childhood irradiation for tinea capitis in a Portuguese cohort. Br J Radiol. 2020 Jan; 93(1105): 20180677. Published online 2020 Jan 1. doi: 10.1259/bjr.20180677 PMCID:PMC6948089 PMID: 31674803.;

Michal Skrzypek, Artur Wdowiak, Lech Panasiuk,Magdalena Stec, Karolina Szczygie³, Ma³gorzata Zyba³a,Micha³ Filip. Effect of ionizing radiation on the female reproductive system. Ann Agric Environ Med. 2019 Dec19;26(4):606-616. doi: 10.26444/aaem/112837. Epub 2019 Nov 12.;

Radiation. volume 100D. A Review of Human Carcinogens. Lyon, France, 2012.;

Radiation and Pregnancy: A Fact Sheet for Clinicians.;

Radiation Protection of the Public and the Environment. General Safety Guide. IAEA Safety Standards Series

No. GSG-8. International Atomic Energy Agency. Vienna, 2018.


Radon and Cancer. (NIH) National Cancer Institute.

Rahul Kumar, Orlando De Jesus. Radiation Effects On The Fetus. In: StatPearls [Internet]. Treasure Island (FL):StatPearls Publishing; 2022 Jan. 2022 Apr 30.;

Siegal Sadetzki, Angela Chetrit, Ben Boursi, Osnat Luxenburg, Ilya Novikov, Arnon Cohen. Childhood Exposure to Low to Moderate Doses of Ionizing Radiation and the Risk of Vascular Diseases. Am J Epidemiol. 2021 Feb 1;190(3):423-430. PMID: 32997139 DOI: 10.1093/aje/kwaa177.


Download data is not yet available.