“RUMIFOS” ANTIOXIDANT POTENTIAL STUDY
In last period, in the world, the demand on netural antioxidants are increased. The main reason of such interest could be that natural antioxidant agents have the wide range of therapeutic effects than synthetized, and also are less toxic. Due to these circumstances, the aim of our work was the substance of product “Rumifos”, which contains the phenolic compounds. As an object for study was taken the three different lots of the research. To study “Rumifos”’ antioxidant activity, we selected the well-established and known combination of spectrophotometric determination of product Absorbance ability (optical density), after reaction of the substance with DPPH-reagent. Method is frequently used to determine the antioxidant potential of the phenolic sums of the plant products. On the basis of the mean optical densities of 10 samples of “Rumifos” substance’s three different batches was calculated the antioxidant activity. At the end of the conducted research work, we can conclude, that product “Rumifos” has quite high antioxidant activity which varies in 70.80-73.83%.
2. Stephanson C.J., Stephanson A.M., Flanegan G.P. Antioxidant capability and efficacy of Mega-H silicahydride, an antioxidant dietary supplement, by in vitro cellular analysis using photosensitization and florescence detection// J of Medicinal Food 2002, #5, p 9-16
3. Srinivas p., Vadhaman M., Arif J., Gupta R. A rapid screening assay of antioxidant potential of natural and synthetic agents in vitro//International Journal of Oncology. 2002. v-20.-p 983-986
4. Diaz-carballo D., Malak S., Bardenheuer W., Freistuehler M., Peter Reusc H. Controbution of Pukentia A to theanti-tumoral activity of Cuban propolis// Bioorg Med Chem. 2008 Nov 15; 16(22):9635-9643.
5. Tanaka T. Falvonoids as complementary medicine for allergic diseases: current evidence and future prospects. OA Alternative Medicine 2013 may 01; 1(2):11.
6. Shashank Kumar and Abhay K. Pandey. Chemistry and biological Activities of Flavonoids. // The JournalScientific World. 2013.- vol. 16.
7. Shahat A.A., Reezah B.S., Bottar R.T.// Phytochemitry.- 2002.#6-p 539-542.
8. Shimizu K1, Das SK, Hashimoto T, Sowa Y, Yoshida T, Sakai T, Matsuura Y, Kanazawa K. Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip1/ p21 expression in human colon cancer cells. Mol Carcinog. 2005 Dec;44(4):293-9.
9. Violi F,Cangemi R.Current Opinion in Investigational Drugs(London, England : 2000) [01 Sep 2005, 6(9):895-900]
10. Barry Halliwell Lipid peroxidation, antioxidants and cardiovascular disease: how should we move forward? Cardiovascular Research, Volume 47, Issue 3, 18 August 2000, Pages 410–418
11. R.HarishT.Shivanandappa. Antioxidant activity and hepatoprotective potential of Phyllanthus niruri. Food Chemistry. Volume 95, Issue 2, March 2006, Pages 180-185