Modern perspectives on the treatment of non-alcoholic fatty liver disease with Metadoxine

Abstract

Non-alcoholic fatty liver disease is a dystrophic dysmetabolic disease of the liver, caused by excessive accumulation of lipids in hepatocytes, with subsequent liver dysfunction and possible cirrhosis. Treatment of this disease should be directed to the risk factors and causes of the development of the disease, as well as to prevent the progression of the pathological process in the liver. In this regard, one of the effective means is metadoxine, which has a pronounced hepatoprotective effect, due to its membrane-stabilizing effect and is based on the ability to restore saturated and unsaturated free fatty acids. The resistance of hepatocytes to lipid peroxidation increases, metadoxine prevents the accumulation of triglycerides in hepatocytes, which significantly slows down the formation of liver cirrhosis.