RESISTANT HYPERTENSION IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

RESISTANT HYPERTENSION IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

Authors

  • ZAHEER AALIF
  • RAVI NARENDRANATH
  • MOHAMMED BILAL MUNEER
  • BASHEER SAFAR

DOI:

https://doi.org/10.52340/jecm.2022.02.12

Abstract

Obstructive sleep apnea (OSA) is a sleep disorder characterised as complete or partial upper airflow cessation during sleep. Although it has been widely accepted that OSA is a risk factor for the development of hypertension, the studies focusing on this topic revealed inconsistent results. We aimed to clarify the association between OSA and resistant hypertension among the population of Calicut district in the state of Kerala. The study was conducted using the STOPBANG questionnaire. All individuals included were between the ages of 35-65 and had previously documented resistant hypertension. The responses from 49 people that fit the inclusion criteria have been analysed. 16/49 of the participants were placed in scores of 0-2, 15/49 were placed in scores of 3-4 and 18/49 were placed in the scores of 5-8. Based on our study, we can conclude that OSA is related to an increased risk of resistant hypertension among the population studied.

Downloads

Download data is not yet available.

Author Biographies

ZAHEER AALIF

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

RAVI NARENDRANATH

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

MOHAMMED BILAL MUNEER

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

BASHEER SAFAR

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

References

Anchala R, Kannuri K, Pant H. et al., Hypertension in India: a systematic review and meta-analysis of prevalence, awareness, and control of hypertension. Hypertension in India, JHypertens,2014;32(6):1170-77.

Buysse DJ Sleep Health: Can We Define It? Does It Matter? Sleep. 2014 Jan 1; 37(1):9-17.

Carey RM, Calhoun DA, Bakris GL, et al., American Heart Association Professional/Public Education and Publications Committee of the Council on Hypertension; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Genomic and Precision Medicine; Council on Peripheral Vascular Disease; Council on Quality of Care and Outcomes Research; and Stroke Council. Hypertension. 2018 Nov; 72(5): e53-e90.

Carey RM, Sakhuja S, Calhoun DA, Whelton PK, Muntner P. Prevalence of Apparent Treatment-Resistant Hypertension in the United States. Hypertension. 2019 Feb; 73(2):424-431.

Dickinson HO, Mason JM, Nicolson DJ, et al. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. J Hypertens. 2006 Feb;24(2):215-33.

Dopp JM, Reichmuth KJ, Morgan BJ Obstructive sleep apnea and hypertension: mechanisms, evaluation, and management. CurrHypertens Rep. 2007 Dec; 9(6):529-34.

Fava C, Dorigoni S, DalleVedove F, Danese E, Montagnana M, Guidi GC, Narkiewicz K, Minuz P. Effect of CPAP on blood pressure in patients with OSA/hypopnea: a systematic review and meta-analysis. Chest 2014; 145(4): 762-77

Garaulet M, Ortega FB, Ruiz JR, et al. Prevalence of short sleep duration and its association with obesity among adolescents 15- to 19-year olds: A cross-sectional study from three major cities in Saudi Arabia. Int J Obes (Lond). 2011 Oct; 35(10):1308-17.

Gupta R, Gaur K, Ram SCV, Emerging trends in hypertension epidemiology in India, Journal of Human Hypertens, 2019(33);8:575–587.

In: Colten HR, Altevogt BM, eds. Sleep disorders and sleep deprivation: an unmet public health problem. Washington (DC), 2006.

Krousel-Wood M, Thomas S, Muntner P, Morisky D. Differences in cardiovascular disease risk when antihypertensive medication adherence is assessed by pharmacy fill versus self-report; The Cohort Study of Medication Adherence among Older Adults (CoSMO). CurrOpinCardiol. 2004 Jul; 19(4):357-62.

Lavie L Obstructive sleep apnoea syndrome-an oxidative stress disorder. SleepMedRev.2003 Feb;7(1):35-51.

Logan AG, Perlikowski SM, Mente A, et al. High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. J Hypertens. 2001 Dec; 19(12):2271-7.

Muxfeldt ES, Margallo V, Costa LM, et al. Hypertension. Effects of continuous positive airway pressure treatment on clinic and ambulatory blood pressures in patients with obstructive sleep apnea and resistant hypertension: a randomized controlled trial. 2015 Apr; 65(4):736-42.

Noubiap JJ, Nansseu JR, Nyaga UF, Sime PS, Francis I, Bigna JJ. Global prevalence of resistant hypertension: a meta-analysis of data from 3.2 million patients. Heart. 2019 Jan; 105(2):98-105.

Pedrosa RP, Drager LF, Gonzaga CC, et al. Obstructive sleep apnea: the most common secondary cause of hypertension associated with resistant hypertension. Hypertension. 2011 Nov; 58(5):811-7.

Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med. 2000; 342

Pimenta E, Stowasser M, Gordon RD, Harding SM, Batlouni M, Zhang B, Oparil S, Calhoun DA. Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism. Chest. 2013;143(4):978–983.

Pratt-Ubunama MN, Nishizaka MK, Boedefeld RL, Cofield SS, Harding SM, Calhoun DA. Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension. Chest. 2007. February;131(2):453–9.

R. Prabhakaran, Trends in hypertension epidemiology in India, J Human Hypertens, 2004(18);2:73–78.

Riegel B, Moelter ST, Ratcliffe SJ, et al. Excessive daytime sleepiness is associated with poor medication adherence in adults with heart failure. J Card Failure. 2011; 17:340–8.

Thunström E, Manhem K, Rosengren A, Peker Y Cardiovascular outcomes of continuous positive airway pressure therapy for obstructive sleep apnea. Am J RespirCrit Care Med. 2016 Feb 1; 193(3):310-20.

Walia HK, Li H, Rueschman M, Bhatt DL, Patel SR, Quan SF, Gottlieb DJ, Punjabi NM, Redline S, Mehra R. Association of severe obstructive sleep apnea and elevated blood pressure despite antihypertensive medication use. J Clin Sleep Med 2014;10(8):835-843.

Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am CollCardiol. 2018 May 15; 71(19): e127-e248.

Zamarrón C, Valdés Cuadrado L, Alvarez-SalaR Pathophysiologic mechanisms of cardiovascular disease in obstructive sleep apnea syndrome. Pulm Med. 2013; 2013:521087.

Zhang J, Ma RC, Kong AP, et al. Relationship of Sleep Quantity and Quality with 24-Hour Urinary Catecholamines and Salivary Awakening Cortisol in Healthy Middle-Aged Adults. Sleep. 2011 Feb 1; 34(2):225-33.

Downloads

Published

2022-04-02

How to Cite

ZAHEER AALIF, RAVI NARENDRANATH, MOHAMMED BILAL MUNEER, & BASHEER SAFAR. (2022). RESISTANT HYPERTENSION IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA. Experimental and Clinical Medicine Georgia, (2). https://doi.org/10.52340/jecm.2022.02.12

Issue

Section

Articles

Most read articles by the same author(s)

Loading...