Study of the alkaloid-containing plants which are grown or introduced in Georgia

Abstract

Was studied constituent of alkaloids in plants which are grown in different regions of Georgia: Kartli, Kakheti, Abkhazeti, Adjara, Svaneti.

Was analysed more than 2500 species, from them 360 species contain alkaloids and 32 species was studied for the first lime. After making of deep chemical researches of the species were isolated 170 pure compounds and among of them 29 compounds have new construction.

More of isolated alkaloids have specific biological and pharmacological activities. Also are isolated chemical groups, which can use for preparing of medical preparations. Were proposed new substances, with antiarrhythmic, spasmolitic, antihistaminic, anticancer, hypoglycaemic and stimulating of leucopoiesls activities. They passed preclinical researches and are recommended for preparing of new medical preparations.