ანოტაცია
Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms including bradykinesia, resting tremor, rigidity, and postural instability. While dopaminergic pharmacotherapy remains the cornerstone of symptom management, long-term use often results in complications such as motor fluctuations and dyskinesias. In this context, device-assisted and lesioning procedures have emerged as viable adjuncts or alternatives to pharmacological interventions.
წყაროები
● UpToDate. Device-assisted and lesioning procedures for Parkinson disease. Retrieved from https://www.uptodate.com/contents/device-assisted-and-lesioning-procedures-for-parkinson-disease
● Lozano, A. M., Lipsman, N., Bergman, H., Brown, P., Chabardes, S., Chang, J. W., ... & Krauss, J. K. (2013). Deep brain stimulation: current challenges and future directions. Neuron, 77(3), 412-430.
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● Lozano, A. M., Snyder, B. J., & Hamani, C. (2012). Deep brain stimulation for Parkinson’s disease: disrupting the disruption. Annals of the New York Academy of Sciences, 1265(1), 22-30.