Abstract
Medicine teaches us that drugs have a temporary effect, while food, sleep and breath have a permanent effect on a person's health. Food products, in addition to trace elements, vitamins and calories-contain substances that activate genes. Especially interesting are the substances that act on the still unconquerable disease — old age. Resveratrol (3,5,4'-trihydroxystilbene) is a natural polyphenol compound. It has the ability to activate SIRT1 and P300 genes. Astaxanthin is a natural pigment that belongs to the carotenoid family. It is also involved in the activation of the SIRT1 gene. Concomitant administration of these two senolytic agents would be expected to result in a cross-effect — the combined effect being greater than the mechanistic sum of their effects.
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