OXIDATIVE STRESS AND ANTIOXIDANTS WITH EMPHASIS ON AGEING (Review Article)

OXIDATIVE STRESS AND ANTIOXIDANTS WITH EMPHASIS ON AGEING (Review Article)

Authors

  • ANAND ANJALI
  • EKA LOMINADZE
  • GURAM MATITASHVILI
  • NIKA KAPANADZE
  • TEKLE DARTSIMELIA
  • TINATIN TKEMALADZE

DOI:

https://doi.org/10.52340/jecm.2022.02.14

Abstract

Numerous theories have been postulated to understand the process of aging. One of them links degenerative senescence to reactive oxygen species (ROS), which are natural byproducts of oxygen metabolism. Understanding and supporting this theory may be of great importance due to number of reasons. Firstly, there are well-established risk factors that can increase the production of ROS in our body. Secondly, there are different types of antioxidants that can neutralize toxic effects of ROS. Examples of antioxidants include natural enzymes produced in our body, as well as certain exogenous supplements. Moreover, antioxidant supplementation is already offered by some facilities as a hope to decrease age-related complications. Therefore, it is crucial to understand, how ROS is involved in the process of aging and if there is any evidence how alteration in ROS and antioxidants levels influence the process of ageing.  

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Author Biographies

ANAND ANJALI

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

EKA LOMINADZE

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

GURAM MATITASHVILI

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

NIKA KAPANADZE

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

TEKLE DARTSIMELIA

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

TINATIN TKEMALADZE

USMD program, Tbilisi State Medical University, Tbilisi, Georgia

Department of Molecular and Medical Genetics, Tbilisi State Medical University, Tbilisi, Georgia

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Published

2022-04-02

How to Cite

ANAND ANJALI, EKA LOMINADZE, GURAM MATITASHVILI, NIKA KAPANADZE, TEKLE DARTSIMELIA, & TINATIN TKEMALADZE. (2022). OXIDATIVE STRESS AND ANTIOXIDANTS WITH EMPHASIS ON AGEING (Review Article). Experimental and Clinical Medicine Georgia, (2). https://doi.org/10.52340/jecm.2022.02.14

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