CALORIMETRIC STUDY OF THE STABILITY OF DPPS-LIPOSOMES AND С AND E VITAMINS COMPLEXES
Abstract
The modem nanotechnology was used to encapsulate vitamins (С, E) in DPPC liposomes. Proportions of vitamins and DPPC lipids were selected as one vitamin per one lipid molecule. The hydrophobic vitamin E was located in hydrophobic part of liposome and the hydrophilic vitamin С - on the surface of a bilayer of liposomes’ membrane. The formation of such complex was confirmed with either calorimetric or biological experiments. In particular, calorimetric curve of the complex differs considerably from calorimetric peak profiles of the pure DPPC liposomes, that further emphasize the existence of vitamins and liposomes complex.
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References
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