POST COVID-19 CONDITION: NEEN FOR CONSENSUS DEFINITION

NANULI  NINASHVILI; IRAKLI  MCHEDLISHVILI; KHATUNA  TCHAAVA; LEVAN  GIORGOBIANI; NATIA  SHAVDIA; NINO  GEGESHIDZE

doi:10.52340/jecm.2022.07.42

POST COVID-19 CONDITION: NEEN FOR CONSENSUS DEFINITION

Authors

NANULI NINASHVILI
IRAKLI MCHEDLISHVILI
KHATUNA TCHAAVA
LEVAN GIORGOBIANI
NATIA SHAVDIA
NINO GEGESHIDZE

DOI:

https://doi.org/10.52340/jecm.2022.07.42

Abstract

During literature review we come across to different definitions of prolonged illness associated with SARS-CoV2 infection, which made it difficult to characterize and compare COVID-19 cases by epidemiological and clinical patterns. Our study is an attempt to assess post-COVID-19 frequency in the context of the case definitions. Prevalence of post-COVID-19 condition ranges from 10% up to 77.8% over the reviewed studies and tends to increase over time along with mutation of the SARS-CoV-2 virus. Consensus definition of Post-COVID Conditions is essential for identification and characterization of clinical, pathophysiological, laboratory, imaging and epidemiologic features of all forms of COVID-19 manifestation. It will help us better understand the disease entity, set up best-practice standards of care and elaborate effective control and preventive measures.

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References

(APTA), American Physical Therapy Association. https://www.apta.org/news/2021/10/19/who-vs-cdc-long-covid-definitions. n.d.

Ana Luiza Cabrera Martimbianco, Rafael Leite Pacheco,Ângela Maria Bagattini,Rachel Riera. "Frequency, signs and symptoms, and criteria adopted for long COVID-19: A systematic review." The International Journal of Clinical Practice (2021): Volume 75, Issue 10, e14357.

CDC. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/post-covid-index.html. n.d.

Chopra V, Flanders SA, O'Malley M, et al. "Sixty- Day Outcomes Among Patients Hospitalized With COVID-19. ." Chopra V, Flanders SA, O'Malley M, Malani AN, Prescott HC. Sixty- Day Outcomes Among Patients Hospi Ann Intern Med. (2020 doi: 10.7326/M20-5661. [PMC free article] [PubMed] [CrossRef] [Google Scholar]).

Fortini A, Torrigiani A, Sbaragli S, et al. "COVID-19: persistence of symptoms and lung alterations after 3-6 months from hospital discharge." Infection. (2021;49(5):): 1007-1015.

Garrigues E, Janvier P, Kherabi Y, et al. " Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19. J Infect." J Infect. (2020;81:e4–e6. doi: 10.1016/j.jinf.2020.08.029. [PMC free article] [PubMed] [CrossRef] [Google Sc).

GCMSC. "Post-Acute COVID. Syndrome (PACS):. Definition, Impact and Management. A Report of the Multidisciplinary. Collaborative Group for the Scientific." June, 2021. <https://www.isglobal.org/documents/10179/7860911/Report+Post-Acute+COVID+Syndrome/58bf2369-c977-4c0a-8fbf-054f2d8df719>.

Grasselli G, Zangrillo A, Zanella A, et al. "COVID-19 Lombardy ICU." JAMA (2020;323:): 1574–81.

Guan WJ, Ni ZY, Hu Y, et al. "China Medical Treatment Expert Group for Covid-19. Clinical characteristics of coronavirus disease 2019 in China." N Engl J Med. (2020;): 1708–20. .

Huang C, Huang L, Wang Y, et al. "Huang C, Huang L, Wang Y, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. ." Lancet. (2021 doi: 10.1016/S0140-6736(20)32656-8. [PMC free article] [PubMed] [CrossRef] [Google Scholar]).

Lledó, Gema M et al. "Post-acute COVID-19 syndrome: a new tsunami requiring a universal case definition." Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases, (2021): S1198-743X(21).000661-3.

Lopez-Leon S, Wegman-Ostrosky T, Perelman C , et al. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. REs SQ [preprint]. 2021 Mar 1 :rs. 3. rs-266574. Update in Sci Rep 2021; 11:16144. PMID: 33688642; PMCID: PMC7941645.

Mark W. Tenforde, Sara S. Kim, Christopher J. Lindsell, et al.,. "Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care System Network — United States, March–June 2020s." Morbidity and Mortality Weekly Report. ( 2020; 69:30.): 994-998.

McGroder CF, Zhang D, Choudhury MA, et al.:. "Pulmonary fibrosis 4 months after COVID-19 is associated with severity of illness and blood leucocyte telomere length." Thorax (2021;76:1242–5).

Munblit D, Nicholson T, Needham D.M., et al. "Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development." BMC Med . (20, 50 (2022)).

Nalbandian A, Sehgal K, Gupta A, et al. "Post-acute COVID-19 syndrome." Nat Med (2021;27:): 601–15.

National Institute for Health and Care Excellence;. "Developing NICE guidelines: the manual. Process and methods PMG20." n.d. https://www.nice.org.uk/process/pmg20/resources/appendix-l-interim-process-and-methods-for-guidelines-developed-in-response-to-heal.

NIH. https://covid19.nih.gov/news-and-stories/when-COVID-19-symptoms-linger. n.d.

ONS. "The prevalence of long COVID symptoms and COVID-19 complications." (16 December 2020). <https://www.ons.gov.uk/news/statementsandletters/theprevalenceoflongcovidsymptomsandcovid19complications>.

P Boscolo-Rizzo, F Guida, J Polesel, et al. "Sequelae in adults at 12 months after mild-to-moderate coronavirus disease 2019 (COVID-19)." Int Forum Allergy Rhinol (2021,).

Quinn KL, Bell CM. "PLoS Med19(1): e1003891." Pandemic health consequences: Grasping the long COVID tail. (2022).

Rando, Halie M et al. "“Challenges in defining Long COVID: Striking differences across literature, Electronic Health Records, and patient-reported information.” medRxiv : the preprint server for health sciences." medRxiv : the preprint server for health sciences (2021.03.20.21253896. 26 Mar. 2021, doi:10.1101/2021.03.20.21253896. Preprint.). <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010765/>.

REZKALLA, S., KLONER, R.. "Post-Acute Sequelae of SARS-COVID-2 Syndrome: Just the Beginning." (2021.): 279-285. <https://cardiologyres.org/index.php/Cardiologyres/article>.

Sebastian Havervall, Axel Rosell, Mia Phillipson, et al.,. "Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers." JAMA, (2021;).

"Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers. JAMA, 2021; DOI: 10.1001/jama.2021.5612."

Sebastian Havervall, Axel Rosell, Mia Phillipson, Sara M. Mangsbo, Peter Nilsson, Sophia Hober, Charlotte Thålin. Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers. JAMA, 2021 and DOI: 10.1001/jama.2021.5612.

Shah, W., Hillman, T., Playford, E. D. & Hishmeh, L. " Managing the long term effects of COVID-19: summary of NICE, SIGN, and RCGP rapid guideline. ." Brit. Med. J. 372, n136 (2021). (n.d.).

Tenforde, Mark W et al. “Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network - United States, March-June 2020.” MMWR. Morbidity and mortality weekly report vol. 6. (n.d.).

Trisha Greenhalgh, Matthew Knight, Christine A’Court, et al. "Management of post-acute covid-19 in primary care." BMJ 2020; 370 (n.d.).

WHO. <https://www.who.int/news-room/events/detail/2021/02/09/default-calendar, WHO New policy brief calls on decision-makers to support patients as 1 in 10 reports symptoms of “long COVID”>.

"A clinical case definition of post COVID-19 condition by a Delphi consensus,." 6 October 2021. <https://www.who.int/publications/i/item/WHO-2019-nCoV-Post_COVID-19_condition-Clinical_case_definition-2021.1>.

"Post COVID-19 condition: A webinar to expand our understanding of this condition." (n.d.). <https://www.who.int/news-room/events/detail/2021/02/09/default-calendar/webinar-post-covid-19-condition>.