The rate of stem cell division decreases with age
PDF (English)

Ключевые слова

stem cells
differentiation
ESC
ASC
apoptosis
ontogenesis
self recovery
senescence
aging

Как цитировать

Tkemaladze, J. (2024). The rate of stem cell division decreases with age. Georgian Scientists, 6(4), 228–242. https://doi.org/10.52340/gs.2024.06.04.21

Аннотация

Intracellular repair and protection mechanisms determine the lifespan of an individual cell. Somatic stem cells determine the lifespan of all tissues and thus play an important role in the aging process of the body. Stem cells possess extensive self-renewal properties, but there is considerable evidence of their decline and erosion over time. The reason why the rate of division of stem cells decreases after each division is not yet determined. Interestingly, stem cells during asymmetric division selectively accumulate, on the one hand, newer molecules and structures, and on the other hand, older centrioles.

https://doi.org/10.52340/gs.2024.06.04.21
PDF (English)

Библиографические ссылки

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